Group photo in the lab

Research

Plant diseases caused by phytopathogenic bacteria pose significant threats to agriculture, impacting both yield and long-term sustainability. In California, woody perennial crops such as plums and almonds are particularly vulnerable, with diseases like plum leaf scald and almond bacterial blast, caused by Xylella fastidiosa and Pseudomonas syringae pv. syringae (Pss) respectively, causing substantial economic losses through reduced yield, compromised tree health, and diminished long-term productivity. Given the limited efficacy and environmental concerns associated with conventional chemical treatments, there is an urgent need for sustainable, targeted disease management strategies. Our research program focuses on developing and optimizing phage-based approaches to control these pathogens, leveraging mechanistic insights into bacterial-phage interactions, host specificity, and phage resistance dynamics to provide growers with environmentally friendly tools that preserve crop health and economic viability.

At the heart of our program are three interconnected areas of focus:

  1. Understanding the biology and genetics of plant–pathogen interactions
  2. Exploring sustainable disease management solutions
  3. Preparing the next generation of scientists to meet future challenges in plant health

 


Plant–Pathogen Interactions


We investigate how bacterial pathogens affect plant health, with a particular focus on woody perennial crops such as almonds, plums, and grapes. By studying the complex interactions between plants and the microbes that challenge them, we aim to uncover the biological and genetic mechanisms underlying disease development, progression, and host specialization. Insights gained from this work provides a foundation for innovative strategies to protect crops, improve resistance, and sustain long-term agricultural productivity. By understanding these fundamental processes, we can better predict disease outbreaks and inform breeding, management, and intervention approaches.

Plant Pathogen Interactions | We investigate how bacterial pathogens affect plant health, with a focus on woody perennial crops.


Sustainable Disease Management Solutions


Our lab is dedicated to developing environmentally friendly and sustainable strategies to manage bacterial diseases in crops. We explore approaches that go beyond traditional chemical treatments, including the use of phage-based therapy. A major focus is on harnessing natural processes to reduce disease pressure while preserving ecosystem health and minimizing environmental impact. This includes evaluating the effectiveness, safety, and scalability of biocontrol solutions under real-world agricultural conditions. Our research contributes to broader global efforts toward resilient and sustainable agriculture, where crop protection strategies align with both productivity and environmental stewardship.

Sustainable disease management solutions graphic


Training the Next Generation


The Olawole lab is deeply committed to mentoring and education, providing meaningful research opportunities for both undergraduate and graduate students. Students gain hands-on experience in plant pathology, microbiology, molecular biology, phage biology and genomics, crop protection, developing practical skills such as pathogen isolation, genome analysis, and experimental design. Beyond technical expertise, we emphasize critical thinking, data interpretation, and scientific communication. Our goal is to inspire and prepare future scientists to tackle complex challenges in plant health and agricultural sustainability, fostering the next generation of leaders in plant pathology, microbiology, and related disciplines. Students also learn how to collaborate across disciplines and engage with real-world problems, preparing them for careers in academia, industry, and agricultural policy.

Prepare future scientists to tackle complex challenges in plant health and agricultural sustainability graphic


Collaborators


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